I've got about 25ft of 10/3 RF ground lead-length for my dedicated line but it is impossible for me to shorten it any, so it is certainly doable with a 10/3. I also have it paralleled with my RF-pass/equalization mains network too though, and that's what makes it a bit more effective than a standalone 10/3 25footer.
In short, don't worry about it too much. Using mains plus makes it really easy to parallel more cables in the future as needed, all you need are standard splitters and extension cords.
You will see an increase by increasing the gauge of the primary side wires though for sure, and it is noticeable, but don't worry about that until you have a solid ground solution. Ohh, and be sure to round off the ends of your strike rail.