It depend from what TTL modulation you have, but in most cases, with no signals on the TTL input, the driver just works as a normal driver, so you can use it a sa normal driver just not connecting anything on the TTL input.
What kind of driver is it? If it's a He-Ne PSU, you have to have power going to the TTL to turn on the laser.
Also some drivers (O-like) need for the TTL to be hooked up, to operate.
Some drivers need a 5V signal to turn on, and others need a 5V signal to turn off. The former is safer and easier for projectors, and the latter is easier for other uses.