My bets are on destroying large planes and outer objects with powerful lasers. Don't think about transporting ourselves with particle physics, instead, we are going to destroy each other with that specialized weaponry and stuff. Vaporizing a man in no time in real life.
I think you would need a powerful laser but even if that works you'll have to point it to its eyes, and that too in a panic situation when encountering a bear. So, I don't think that's a safe option against a revolver or a weapon or a simple fire.