Age-related Macular Degeneration (AMD) is a condition of advanced degeneration of the macular portion of the retina that leads to progressive blindness in over 35% of persons over the age of 75.1 AMD has been linked to the stress engendered by radical oxygen species in macular photoreceptor cells and proximate retinal pigment epithelium cells (RPE).2 Both of these types of cells are non-replicating (post-mitotic) and must respond to a lifetime of oxidative insult, which includes light-induced oxidative stress.3 While there are numerous mechanisms in the retina for preventing and forestalling oxidative insult, by middle-age many of these anti-oxidative mechanisms have begun to break down, which increases the susceptibility of the retina to accumulated damage with increasing age.4
Visible light absorbed by photoreceptors is a significant factor in the production of reactive oxygen species that induce the molecular damage in retinal tissue which appears to contribute to the formation of AMD.5 To an overwhelming degree, blue wavelengths of light produce the most oxidative stress within the retina and are primarily responsible for exacerbating the extent of oxidative damage that has begun to occur.6 Since blue light wavelengths impart the greatest risk of photochemical damage, the risk of retinal damage from light is termed "the blue light hazard", with the greatest hazard peaking at wavelength of 440 nm.7
Yeah, but think of the amount of time you spend looking at the screen vs the amount of time looking at the spot of a 445nm laser. You shouldn't be looking at the spot of a 500mw+ laser up-close anyway without goggles. That's just asking to go blind.Not nearly as concentrated as 500-1000 mW of laser light.
I'd hazard you're gonna get a lot more retinal bleaching looking at the spot of a powerful laser compared to your computer monitor.
So how much blue exposure does it take to weaken the visibility of green light anyway, and does it last for a while or does it go away in a few minutes/hours. Im not talking about accidents or hits, just exposure to excess 445nm in class IV powers with normal use. Its almost like green isnt as bright as I remembered it, but is it because I am used to it now, or because of the 445nm?